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Flumioxazin is a registered herbicide for agricultural crops what is an important fact concerning integrated management for weeds in eucalyptus plantations. This study evaluated the efficiency of weed control and the phytotoxicity in eucalyptus plants caused by the herbicide flumioxazin applied alone or in tank mixture with sulfentrazone and isoxaflutole. The aim was to extend the use of this herbicide in eucalyptus. The herbicide was applied to eucalyptus plants using precision backpack sprayer. It was evaluated, visually, the intoxication percentage and measured height and diameter of eucalyptus trees, the control plants and dry mass of weeds. It was concluded that flumioxazin is selective to the eucalyptus at the 125 g.ha-1 dosage, and its efficiency in controlling weeds pre-emergence was better when mixed in the tank with isoxaflutole and sulfentrazone.